Mapping Normative Frameworks for EThics and Integrity of Research (EnTIRE)

The EnTIRE project (Mapping Normative Frameworks for EThics and Integrity of Research) has received a 4 million euros Horizon 2020 (EU) funding. The project is coordinated by VUmc and will be carried out by an international consortium spanning ten countries worldwide (a.o. United Kingdom, Belgium, Norway, Germany and the United States). The coordinating team consists of Prof. Guy Widdershoven (head of the VUmc department of Medical Humanities), Prof. Lex Bouter (VUmc department of Epidemiology and Biostatistics), Dr. Natalie Evans (VUmc department of Public and Occupational Health), Marc van Hoof, MD (Department of Medical Humanities) and Laura Hartman, MA (Department of Medical Humanities/Metamedica). Of the 4 million, 1.2 million will be assigned to VUmc.

The aim of the EnTIRE project is to create a platform that makes normative framework governing for Research Ethics and Research Integrity (RE+RI) easily accessible, supports application in research and evaluation, and involves all stakeholders in a participatory way, thus achieving sustainability.

Read the project summary

Distinguishing and predicting end-of-life trajectories in older people

Natalie received a Quality of Care Fellowship to undertake a study on end-of-life trajectories in older people. This study aims to distinguish, understand and predict different end-of-life trajectories in older people. Not only are physical and cognitive trajectories estimated, but also decedents’ care use, and associated costs, to identify main trajectories/pathways. Socio-demographic and health factors associated with trajectory groups are also examined.

This study draws on data from two longitudinal cohort studies (LASA and InterRAI) and data from health insurance claims (Achmea). LASA and Achmea provide fairly representative samples of the Dutch population, whereas InterRAI provides a sample of long-term care residents. 

Full project description


Natalie received a Marie Curie Fellowship (2011-2014) to take part in the EuroImpact project. The European Intersectorial and Multidisciplinary Palliative Care Research Training aimed to develop a multidisciplinary, multi-professional and intersectorial educational and research training framework in Europe, aimed at monitoring and improving the quality of palliative care in Europe.

EuroImpact website


Natalie worked as a Research Fellow on the EU supported PRISMA programme (Fp7) on the work package concerning the influence of culture on end-of-life care 2008-2011.

PRISMA programme which aimed to inform best practice and harmonise research in end-of-life (EoL) care for cancer patients across Europe.

PRISMA website