Opti-Med study

The objective of the Opti-Med study is to establish the (cost-)effectiveness of a structured medication review and monitoring of the medication used by patients aged 65 and over who present with a new ‘geriatric giant’ problem in general practice.

‘Geriatric giants’ are mobility and stability problems, incontinence or cognitive problems. About 25% of the patients of 65 years or older consult their GP in a year with a new problem that is related to a geriatric giant. In elderly patients these geriatric problems often co-occur with existing chronic diseases and changes in pharmacokinetics and -dynamics. These are all risk factors for suboptimal pharmacotherapy and medication-related problems.

In 2014 a study on an innovative medication review method has started in 25 general practices of the Academic Network of General Practitioner (ANH-Vumc) of the VU medical Centre in Amsterdam.

In a cluster-randomized controlled study, a centrally organised approach of a structured medication review program in 500 patients with geriatric complaints will be investigated.

Primary outcome measures are quality of life and changes in the presented geriatric giant. Secondary outcome measures include medication satisfaction, number of drug related problems (DRPs), medication adherence and health care costs. In addition, the success and failure factors for this new form of medication review will be investigated in a process analysis study.

This study is a collaboration between the EMGO+ Institute for Health and Care Research at VU University Medical Center Department of general practice & elderly care medicine and NIVEL (Netherlands Institute for Health Services Research)